INT243934

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.63
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fibp) biological_process (Fibp)
Fibp (Mus musculus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 1 81.92 Quite High
GABAergic 31 50.00 Quite Low
GABA receptor 2 14.48 Low Low
Glutamate receptor 7 11.52 Low Low
gABA 28 5.00 Very Low Very Low Very Low
midbrain 26 5.00 Very Low Very Low Very Low
Glutamate 18 5.00 Very Low Very Low Very Low
Neurotransmitter 11 5.00 Very Low Very Low Very Low
Kinase C 10 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Starvation 1 99.12 Very High Very High Very High
Apoptosis 3 98.52 Very High Very High Very High
Disease 89 68.72 Quite High
Stress 13 63.68 Quite High
Aging 15 61.36 Quite High
Cancer 3 60.80 Quite High
Targeted Disruption 9 60.56 Quite High
Neurodegenerative Disease 6 59.36 Quite High
Parkinson's Disease 42 44.60 Quite Low
Toxicity 5 21.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Autophagy is responsible for the majority of intracellular protein degradation in particular during starvation and apoptosis.
Protein_catabolism (degradation) of intracellular protein associated with starvation and apoptosis
1) Confidence 0.01 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0.26 Pain Relevance 0.04
The two principal pathways of intracellular protein degradation are the UPS, responsible for the bulk of the turnover of short-lived cytosolic proteins, and the autophagy–lysosome pathway (ALP), involved in the degradation of long-lived stable proteins as well as in the recycling of organelles (Jellinger, 2009).
Protein_catabolism (degradation) of intracellular protein
2) Confidence 0.01 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2978035 Disease Relevance 0.37 Pain Relevance 0

General Comments

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