INT243935

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gabarap) Golgi apparatus (Gabarap) plasma membrane (Gabarap)
cytoskeleton (Gabarap) lysosome (Gabarap) cytoplasm (Gabarap)
Anatomy Link Frequency
synapses 1
Gabarap (Mus musculus)
Pain Link Frequency Relevance Heat
GABA receptor 2 83.28 Quite High
Kinase C 11 63.00 Quite High
GABAergic 30 50.00 Quite Low
Hippocampus 6 10.08 Low Low
depression 17 6.80 Low Low
gABA 39 5.00 Very Low Very Low Very Low
Neurotransmitter 9 5.00 Very Low Very Low Very Low
Glutamate 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Glutamate receptor 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 7 44.64 Quite Low
Depression 17 6.80 Low Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We recently reported that a CaMKII-mediated sustained conformational change of GABAAR-associated protein (GABARAP), which directly binds to GABAAR ?
Localization (change) of GABARAP
1) Confidence 0.73 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2710870 Disease Relevance 0 Pain Relevance 0.03
GABARAP is mainly localized in intracellular compartments, such as endoplasmatic reticulum, Golgi structures and intracellular vesicles near the synapses, but only a small fraction is directly colocalized with synaptic GABAA receptors (Kittler and Moss, 2001; Kneussel and Betz, 2000; Leil et al., 2004).
Localization (localized) of GABARAP in synapses
2) Confidence 0.36 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.07

General Comments

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