INT243940

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.88
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gabrg2) plasma membrane (Gabrg2) cytoplasm (Gabrg2)
Gabrg2 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 16 100.00 Very High Very High Very High
Kappa opioid receptor 1 96.84 Very High Very High Very High
gABA 48 96.72 Very High Very High Very High
Hippocampus 34 87.12 High High
Pyramidal cell 6 80.16 Quite High
GABAergic 32 50.00 Quite Low
Glutamate 21 47.60 Quite Low
GABA receptor 3 37.24 Quite Low
agonist 7 23.36 Low Low
Kinase C 10 14.20 Low Low
Disease Link Frequency Relevance Heat
Injury 66 93.36 High High
Targeted Disruption 9 83.32 Quite High
Brain Injury 62 82.96 Quite High
Starvation 1 51.36 Quite High
Apoptosis 12 50.16 Quite High
Cognitive Disorder 6 14.36 Low Low
Depression 9 5.00 Very Low Very Low Very Low
Convulsion 6 5.00 Very Low Very Low Very Low
Epilepsy 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There may be diverse regulatory mechanisms involved in the interaction between NMDA receptors and GABAAR.
GABAAR Binding (interaction) of associated with nmda receptor
1) Confidence 0.47 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2893123 Disease Relevance 0.69 Pain Relevance 0.52
Another family member is GEC-1, that like GABARAP binds the gamma2 subunit, tubulin and NSF and plays an important role in surface expression of kappa-opioid receptors (Chen et al., 2006).
gamma2 Binding (binds) of associated with kappa opioid receptor
2) Confidence 0.11 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0.18 Pain Relevance 0.05

General Comments

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