INT243966

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein targeting (Trak2) plasma membrane (Trak2) nucleus (Trak2)
enzyme binding (Trak2) cytoplasm (Trak2)
Anatomy Link Frequency
fibroblast 1
Trak2 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 117 87.96 High High
gABA 112 5.00 Very Low Very Low Very Low
Kinase C 40 5.00 Very Low Very Low Very Low
Neurotransmitter 36 5.00 Very Low Very Low Very Low
depression 32 5.00 Very Low Very Low Very Low
Glutamate 32 5.00 Very Low Very Low Very Low
Glutamate receptor 24 5.00 Very Low Very Low Very Low
Hippocampus 24 5.00 Very Low Very Low Very Low
Nucleus accumbens 20 5.00 Very Low Very Low Very Low
Action potential 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 41.32 Quite Low
Osteogenic Sarcomas 1 11.60 Low Low
Depression 32 5.00 Very Low Very Low Very Low
Targeted Disruption 29 5.00 Very Low Very Low Very Low
Anxiety Disorder 16 5.00 Very Low Very Low Very Low
Myopia 13 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low
Epilepsy 8 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 8 5.00 Very Low Very Low Very Low
Adhesions 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Six genes were chosen to confirm the temporal expression analysis: fibroblast growth factor 13 (Fgf13) mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), trafficking protein, kinesin binding 2 (Trak2), Jagged 1 (Jag1), serine/threonine kinase 3 (Stk3), and kruppel-like factor 9 (Klf9).


Trak2 Binding (binding) of in fibroblast
1) Confidence 0.34 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0 Pain Relevance 0
Interaction between GABAA receptors and GRIF-1 has not been demonstrated in vivo and no functional studies have yet been carried out to directly address what role this protein may have in regulating GABAA receptor function.


GRIF-1 Binding (Interaction) of
2) Confidence 0.06 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.03
GABAA receptor interacting factor-1 (GRIF-1)
GRIF-1 Binding (interacting) of
3) Confidence 0.06 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.04
The role of GRIF-1 in regulating GABAAR function remains unclear, however it can interact directly with kinesin motor proteins (Brickley et al., 2005).
GRIF-1 Binding (interact) of
4) Confidence 0.05 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.04
GRIF-1 was identified as a protein interacting with the beta2 subunit (Beck et al., 2002).
GRIF-1 Binding (interacting) of
5) Confidence 0.04 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox