INT243970

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tfap2a) Golgi apparatus (Tfap2a) nucleus (Tfap2a)
DNA binding (Tfap2a) transcription factor binding (Tfap2a) cytoplasm (Tfap2a)
Tfap2a (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 5 94.36 High High
GABAergic 29 93.80 High High
agonist 6 93.12 High High
Dopamine 3 86.20 High High
Serotonin 1 76.36 Quite High
Kinase C 10 75.04 Quite High
Glutamate receptor 6 57.56 Quite High
depression 8 17.04 Low Low
Hippocampus 8 10.16 Low Low
gABA 28 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 14 80.40 Quite High
Disease 154 74.40 Quite High
Death 8 55.68 Quite High
Depression 8 17.04 Low Low
Parkinson's Disease 1 13.44 Low Low
Stress 28 7.20 Low Low
Targeted Disruption 38 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 22 5.00 Very Low Very Low Very Low
Syndrome 15 5.00 Very Low Very Low Very Low
Cognitive Disorder 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It also contains a variety of transcription factor binding sites, including those for Sp1, GATA-1, AP1, AP2, CREB, estrogen and glucocorticoid receptors, NF?
Phosphorylation (those) of AP2
1) Confidence 0.25 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 0.56 Pain Relevance 0
PKA negatively regulates the endocytosis of the GABAA receptor via phosphorylation of an atypical binding motif for the clathrin AP-2 adaptor complex (see below).
Phosphorylation (phosphorylation) of AP-2
2) Confidence 0.05 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.56

General Comments

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