INT244039

Context Info Confidence 0.09 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.10

plasma membrane (Gabrg1, Gphn) cytoskeletal protein binding (Gphn) transport (Gabrg1) cytoskeleton (Gphn) intracellular (Gphn) cytoplasm (Gphn)

Gabrg1 (Mus musculus) Gphn (Mus musculus)

Pain Link Frequency Relevance Heat GABAergic 29 71.84 Spinal cord 1 70.04 medulla 2 23.76 gABA 28 5.00 Kinase C 10 5.00 Neurotransmitter 9 5.00 depression 8 5.00 Glutamate 8 5.00 Glutamate receptor 6 5.00 Hippocampus 6 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 7 86.16 Respiratory Failure 1 19.16 Depression 8 5.00 Anxiety Disorder 4 5.00 Generalized Anxiety Disorder 2 5.00 Stress 2 5.00 Epilepsy 2 5.00 Necrosis 1 5.00 Adhesions 1 5.00 Cognitive Disorder 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Recently it has been demonstrated that gephyrin is capable of a detergent sensitive direct interaction with GABAA receptor alpha subunits (Tretter et al., 2008).

GABAA receptor Binding (interaction) of gephyrin

1) Confidence 0.09 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0.16 Pain Relevance 0.10

General Comments

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