INT244046

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gabrg1, Prkca) mitochondrion (Prkca) transport (Gabrg1)
endoplasmic reticulum (Prkca) enzyme binding (Prkca) protein complex (Prkca)
Gabrg1 (Mus musculus)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 10 100.00 Very High Very High Very High
Glutamate receptor 6 97.16 Very High Very High Very High
Serotonin 1 71.92 Quite High
GABAergic 29 70.56 Quite High
Dopamine 3 58.96 Quite High
Nucleus accumbens 5 55.60 Quite High
agonist 4 38.32 Quite Low
gABA 28 27.68 Quite Low
Neurotransmitter 9 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Premenstrual Syndrome 1 33.16 Quite Low
Anxiety Disorder 4 6.48 Low Low
Depression 8 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Protein kinase C (PKC) is recruited to the GABAA receptor via the anchoring protein RACK-1 and similar to PKA has different effects on receptor function depending on the subunit composition (Brandon et al., 2002; Connolly et al., 1999; Herring et al., 2005; Jovanovic et al., 2004; Krishek et al., 1994; Leidenheimer et al., 1992; Lin et al., 1996; Poisbeau et al., 1999).
GABAA receptor Binding (recruited) of PKC associated with kinase c
1) Confidence 0.06 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526003 Disease Relevance 0 Pain Relevance 0.39

General Comments

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