INT244147

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.63
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NLRP12) cytoplasm (NLRP12)
NLRP12 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 3 77.12 Quite High
cytokine 14 37.04 Quite Low
Inflammation 8 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
interstitial cystitis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 93 98.04 Very High Very High Very High
Cancer 85 67.68 Quite High
Disorder Of Lipid Metabolism 3 46.24 Quite Low
Breast Cancer 3 36.08 Quite Low
Congenital Anomalies 3 34.64 Quite Low
Apoptosis 11 33.88 Quite Low
Aneuploidy 3 21.56 Low Low
Chromosome Aberrations 9 19.16 Low Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Stress Incontinence 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our assays did not detect Nalp4, Nalp6, or Nalp12 either in HCE-T or in primary corneal cells, although the corresponding assays were verified by using other cell types that expressed these genes (data not shown).
Neg (not) Gene_expression (detect) of Nalp12
1) Confidence 0.45 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0 Pain Relevance 0
Paradoxically, the striking gene expression profile differences between bNO and rNO did not imply the differences in regional gene expression bias (see Figure 1).
Gene_expression (expression) of rNO
2) Confidence 0.13 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC3022544 Disease Relevance 0.05 Pain Relevance 0
Among the genes differentially expressed between bNO and rNO, a significant number are sodium-related (15 genes in total), involving functions related to sodium transportation (sodium ion binding, sodium ion transportation).
Gene_expression (expressed) of rNO
3) Confidence 0.11 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC3022544 Disease Relevance 0.38 Pain Relevance 0.04
Tissues for rNO cases were obtained from the same institute as those for rUCs; their microarray data were scanned using the same facility and in roughly the same time period as data for rUC samples.
Gene_expression (cases) of rNO
4) Confidence 0.11 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC3022544 Disease Relevance 0.20 Pain Relevance 0

General Comments

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