INT244149

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.99
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (RNGTT) nucleoplasm (RNGTT) nucleus (RNGTT)
nucleotidyltransferase activity (RNGTT)
Anatomy Link Frequency
T cells 6
RNGTT (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 97.56 Very High Very High Very High
cytokine 42 97.04 Very High Very High Very High
agonist 9 5.00 Very Low Very Low Very Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 36 97.56 Very High Very High Very High
Death 3 87.44 High High
Apoptosis 24 84.72 Quite High
Malignant Neoplastic Disease 3 83.48 Quite High
Skin Cancer 3 81.00 Quite High
Reprotox - General 1 3 80.48 Quite High
Cancer 3 78.56 Quite High
Hyperplasia 3 74.64 Quite High
Toxicity 3 52.96 Quite High
Infection 15 7.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our studies, the effect of UV light on the expression of the monitored NLR molecules in the HCE-T cells was different at early (6 h) and late (24 h) time points, and it also resulted in different changes of Nalps and Nods expression.
Regulation (effect) of Gene_expression (expression) of HCE in T cells
1) Confidence 0.13 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0.84 Pain Relevance 0
These results show that the cellular response detected by transcriptional changes of NLR expression in HCE-T cells is accompanied by the enhanced secretion of the pro-inflammatory cytokine, IL-6, but not that of the biologically active IL-1?
Regulation (changes) of Gene_expression (expression) of HCE in T cells associated with inflammation and cytokine
2) Confidence 0.13 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0.15 Pain Relevance 0.26
Effect of UV-B irradiation on the expression of Nod subtypes in HCE-T cells
Regulation (Effect) of Gene_expression (expression) of HCE in T cells
3) Confidence 0.13 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0 Pain Relevance 0

General Comments

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