INT244171

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NOD1) signal transduction (NOD1) plasma membrane (NOD1)
intracellular (NOD1) cytoplasm (NOD1)
Anatomy Link Frequency
head 1
T cells 1
NOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 28 97.28 Very High Very High Very High
agonist 6 96.64 Very High Very High Very High
Inflammation 16 33.68 Quite Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 16 34.60 Quite Low
INFLAMMATION 24 33.68 Quite Low
Infection 10 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Uveitis 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Wrinkles 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results imply that unlike the case of Nalps, there is a general early and long-term downregulation of the Nod sensors after UV-B irradiation.


Negative_regulation (downregulation) of Nod
1) Confidence 0.47 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0 Pain Relevance 0.16
While UV-B irradiation exerted a downregulation of both Nalp and Nod mRNAs as well as those of inflammasome components in HCE-T cells, longer incubation of the cells after exposure resulted in recovery or upregulation only of the Nalp sensors.
Negative_regulation (downregulation) of Nod in T cells
2) Confidence 0.34 Published 2008 Journal Molecular Vision Section Abstract Doc Link PMC2526096 Disease Relevance 0 Pain Relevance 0.12
Modeling the interaural tVOR and the effect of Nod/Uv lesions: impaired integration of head acceleration
Negative_regulation (effect) of Nod/Uv in head
3) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981566 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox