INT244175

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Context Info
Confidence 0.53
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.19
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CARD8) intracellular (CARD8) cytoplasm (CARD8)
Anatomy Link Frequency
T cells 1
CARD8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 37 84.92 Quite High
Inflammatory response 4 36.76 Quite Low
spastic colon 25 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 71 94.96 High High
Inflammatory Bowel Disease 118 85.84 High High
INFLAMMATION 35 84.92 Quite High
Colitis 15 56.32 Quite High
Enteropathy 5 53.44 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

25 5.00 Very Low Very Low Very Low
Recurrence 9 5.00 Very Low Very Low Very Low
Apoptosis 9 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression level of ASC adaptor was more than two orders of magnitude lower in HCE-T cells as compared to that measured in the PRK samples whereas the expression of Cardinal, a specific adaptor of the Nalp3 inflammasome, was similar in the two cell types.
Gene_expression (expression) of Cardinal in T cells
1) Confidence 0.53 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2526096 Disease Relevance 0 Pain Relevance 0
Genetic (NOD2, NOD1, TLR4, CARD8) and new serologic markers (ASCA, ACMA, ALCA, ACCA, ASigmaMA, OmpC, CBir1, I2) were analyzed in all of the subjects.
Spec (analyzed) Gene_expression (Genetic) of CARD8
2) Confidence 0.40 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2827710 Disease Relevance 1.19 Pain Relevance 0.04

General Comments

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