INT244183

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.71
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (MRC1) plasma membrane (MRC1)
Anatomy Link Frequency
germline 2
MRC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 94.80 High High
abdominal pain 5 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Togavirus Infection 53 100.00 Very High Very High Very High
Immunization 6 100.00 Very High Very High Very High
Hereditary Nonpolyposis Colorectal Neoplasms 22 98.12 Very High Very High Very High
Colorectal Cancer 100 96.24 Very High Very High Very High
INFLAMMATION 5 94.80 High High
Carcinoma 32 89.16 High High
Syndrome 77 80.80 Quite High
Disease 1 80.48 Quite High
Cancer 62 80.44 Quite High
Autism 17 69.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If this model is correct, MMR immunization should precede GI complaints, and both MMR and GI complaints should precede onset of ASD.
Localization (immunization) of MMR associated with immunization and togavirus infection
1) Confidence 0.49 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2526159 Disease Relevance 1.13 Pain Relevance 0.05
The MMR genes mutated in the germline in HNPCC have been identified so far as hMSH2 (located on 2p), hMLH1 (located on 3p), hPMS1, hPMS2 and hMSH6.
Localization (located) of MMR in germline
2) Confidence 0.15 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 1.29 Pain Relevance 0
The MMR genes mutated in the germline in HNPCC have been identified so far as hMSH2 (located on 2p), hMLH1 (located on 3p), hPMS1, hPMS2 and hMSH6.
Localization (located) of MMR in germline
3) Confidence 0.15 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 1.29 Pain Relevance 0

General Comments

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