INT244289

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
nucleus (Jak1) cytoplasm (Jak1)
Anatomy Link Frequency
brain 2
Il6 (Rattus norvegicus)
Jak1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 11 92.56 High High
Hippocampus 11 51.24 Quite High
cytokine 6 31.68 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 11 92.56 High High
Stress 3 35.84 Quite Low
Delirium 7 5.00 Very Low Very Low Very Low
Sepsis 5 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, as IL-6 induces HO-1 mRNA through the JAK/stat pathway in the liver (Tron et al 2006), this mechanism may also work in the brain.
IL-6 Positive_regulation (induces) of Gene_expression (pathway) of JAK in brain
1) Confidence 0.38 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2526382 Disease Relevance 0.09 Pain Relevance 0.07

General Comments

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