INT244328

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.26
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ELF3, SH3GL3) endosome (SH3GL3) Golgi apparatus (ELF3)
extracellular matrix organization (ELF3) embryo development (ELF3) lipid binding (SH3GL3)
Anatomy Link Frequency
urine 3
endothelium 2
plasma 1
ELF3 (Homo sapiens)
SH3GL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 6 87.44 High High
Pain 15 36.40 Quite Low
Pain score 3 13.12 Low Low
Paracetamol 4 11.08 Low Low
Central nervous system 7 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
carbamazepine 2 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fabry Disease 90 98.40 Very High Very High Very High
Proteinuria 91 93.60 High High
Fibrosis 6 87.44 High High
Albuminuria 4 85.72 High High
Disease 36 80.72 Quite High
Renal Disease 43 50.00 Quite Low
Pain 18 36.40 Quite Low
Hypohidrosis 11 35.36 Quite Low
Diarrhoea 4 33.92 Quite Low
Neurologic Manifestations 4 15.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ERT resulted in decreased plasma and urine GL-3 levels even after a short-term treatment, and reduced GL-3 accumulation in various organs and tissues (24).
ERT Negative_regulation (reduced) of Positive_regulation (accumulation) of GL-3 in urine
1) Confidence 0.20 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526436 Disease Relevance 0.35 Pain Relevance 0
ERT was shown to reduce GL-3 accumulation in dermal endothelium in children with Fabry disease (Wraith et al 2008).
ERT Negative_regulation (reduce) of Positive_regulation (accumulation) of GL-3 in endothelium associated with fabry disease
2) Confidence 0.11 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727881 Disease Relevance 0.57 Pain Relevance 0.04
ERT resulted in decreased plasma and urine GL-3 levels even after a short-term treatment, and reduced GL-3 accumulation in various organs and tissues (24).
ERT Negative_regulation (reduced) of in plasma Positive_regulation (accumulation) of GL-3 in urine
3) Confidence 0.07 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526436 Disease Relevance 0.35 Pain Relevance 0

General Comments

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