INT244344

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 12
Total Number 12
Disease Relevance 6.72
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (Rbmy1a1) mRNA processing (Rbmy1a1) RNA binding (Rbmy1a1)
nucleus (Rbmy1a1)
Anatomy Link Frequency
thickening 2
Rbmy1a1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 64 89.28 High High
corticosteroid 14 78.80 Quite High
Inflammation 98 75.36 Quite High
alcohol 11 49.04 Quite Low
lidocaine 33 33.52 Quite Low
cytokine 2 5.00 Very Low Very Low Very Low
algil 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 762 99.52 Very High Very High Very High
Airway Obstruction 4 98.08 Very High Very High Very High
Perennial Allergic Rhinitis 11 97.76 Very High Very High Very High
Eczema 11 97.76 Very High Very High Very High
Disease 16 97.16 Very High Very High Very High
Rhinitis 55 95.80 Very High Very High Very High
Occupational Lung Diseases 61 92.44 High High
Fibrosis 64 89.28 High High
Cough 44 80.24 Quite High
Respiratory Sounds 33 79.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is obvious that for this reason the interpretation of the finding is difficult and it could imply that RBM thickening might not be such an important agent affecting airway obstruction.
Gene_expression (thickening) of RBM in thickening associated with airway obstruction
1) Confidence 0.14 Published 2008 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2805797 Disease Relevance 0.65 Pain Relevance 0.21
Thus, we are able to exclude the possibility that the RBM thickening observed in asymptomatic AHR subjects was a feature of atopic rhinitis.
Gene_expression (thickening) of RBM in thickening associated with perennial allergic rhinitis
2) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 1.57 Pain Relevance 0.03
Assessment of RBM thickness
Gene_expression (thickness) of RBM
3) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.40 Pain Relevance 0
In terms of mean, minimum, and maximum values, RBM thicknesses were greater in asymptomatic AHR with atopy than in asymptomatic AHR without atopy or in normal controls.
Gene_expression (thicknesses) of RBM associated with asthma
4) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 1.31 Pain Relevance 0.15
No significant differences were observed between the atopic asymptomatic AHR group and mild atopic asthma group in terms of mean RBM thicknesses (p>0.05, Fig. 1), nor between the non-atopic asymptomatic AHR group and the two control groups in terms of mean RBM thicknesses (p>0.05, Fig. 1).


Gene_expression (thicknesses) of RBM associated with asthma
5) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.32 Pain Relevance 0
Mean RBM thicknesses were significantly higher in the mild atopic asthma group and the atopic asymptomatic AHR group than in the other three groups (p=0.048, Fig. 1, 2), which is also in minimum RBM thicknesses (p=0.037).
Gene_expression (thicknesses) of RBM associated with asthma
6) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.41 Pain Relevance 0
On EM, mean RBM thicknesses were 4.3±1.7 µm in the mild atopic asthma group, 3.4±1.8 µm in the atopic asymptomatic AHR group, 2.5±1.5 µm in the non-atopic asymptomatic AHR group, 2.6±1.1 µm in the atopic controls, and 2.3±1.2 µm in the non-atopic controls (p=0.002, Fig. 1).
Gene_expression (thicknesses) of RBM associated with asthma
7) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.40 Pain Relevance 0
Corresponding maximum RBM thicknesses were 5.5±1.6 µm, 4.5±1.8 µm, 3.5±1.3 µm, 3.4±0.8 µm, and 3.1±0.9 µm, respectively (p=0.002), and corresponding minimum RBM thicknesses were 3.0±0.7 µm, 2.3± 1.0 µm, 1.6±0.8 µm, 1.9±0.9 µm, and 1.4±0.7 µm, respectively (p=0.015).
Gene_expression (thicknesses) of RBM
8) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.38 Pain Relevance 0
Mean RBM thicknesses were significantly higher in the mild atopic asthma group and the atopic asymptomatic AHR group than in the other three groups (p=0.048, Fig. 1, 2), which is also in minimum RBM thicknesses (p=0.037).
Gene_expression (thicknesses) of RBM associated with asthma
9) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.42 Pain Relevance 0
No significant differences were observed between the atopic asymptomatic AHR group and mild atopic asthma group in terms of mean RBM thicknesses (p>0.05, Fig. 1), nor between the non-atopic asymptomatic AHR group and the two control groups in terms of mean RBM thicknesses (p>0.05, Fig. 1).


Gene_expression (thicknesses) of RBM associated with asthma
10) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.32 Pain Relevance 0
Corresponding maximum RBM thicknesses were 5.5±1.6 µm, 4.5±1.8 µm, 3.5±1.3 µm, 3.4±0.8 µm, and 3.1±0.9 µm, respectively (p=0.002), and corresponding minimum RBM thicknesses were 3.0±0.7 µm, 2.3± 1.0 µm, 1.6±0.8 µm, 1.9±0.9 µm, and 1.4±0.7 µm, respectively (p=0.015).
Gene_expression (thicknesses) of RBM
11) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.42 Pain Relevance 0
Age, atopic index, FEV1, FVC, RBM, and subepithelial layer thickness results are expressed as means±SD.
Gene_expression (expressed) of RBM
12) Confidence 0.03 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.11 Pain Relevance 0.03

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