INT244396

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc12a2)
Anatomy Link Frequency
neurons 1
Cl (Mus musculus)
Slc12a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nociceptor 12 97.92 Very High Very High Very High
Pain 2 95.16 Very High Very High Very High
allodynia 4 90.16 High High
Inflammation 18 65.36 Quite High
intrathecal 1 62.80 Quite High
Hyperalgesia 12 60.20 Quite High
Inflammatory mediators 46 50.00 Quite Low
Dorsal horn 2 49.92 Quite Low
gABA 15 5.00 Very Low Very Low Very Low
substance P 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 12 97.64 Very High Very High Very High
Pain 2 95.16 Very High Very High Very High
Neuropathic Pain 5 90.16 High High
Pruritus 1 84.72 Quite High
Nervous System Injury 1 79.12 Quite High
Neurogenic Inflammation 2 66.24 Quite High
Hyperalgesia 12 60.20 Quite High
Peripheral Arterial Disease 4 53.04 Quite High
INFLAMMATION 66 50.00 Quite Low
Ganglion Cysts 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genetic ablation of the Na+-K+-2Cl- cotransporter NKCC1 was associated with reduced Cl- accumulation in DRG neurons and caused a reduced thermal nociceptive response [13] as well as attenuation of A?
Cl Binding (associated) of NKCC1 in neurons associated with nociception
1) Confidence 0.03 Published 2008 Journal Mol Pain Section Body Doc Link PMC2526990 Disease Relevance 0.88 Pain Relevance 0.76

General Comments

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