INT244404

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 21
Total Number 22
Disease Relevance 35.88
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (HEPACAM) cell cycle (HEPACAM) cytoplasm (HEPACAM)
Anatomy Link Frequency
cervix 10
HEPACAM (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 20 67.28 Quite High
imagery 4 51.16 Quite High
Central grey 1 24.64 Low Low
Spinal cord 3 7.44 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cervical Cancer 1957 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1637 100.00 Very High Very High Very High
Cancer 501 100.00 Very High Very High Very High
Breast Cancer 154 100.00 Very High Very High Very High
Scoliosis 113 100.00 Very High Very High Very High
Infection 286 99.92 Very High Very High Very High
Genital Human Papilloma Virus 608 99.72 Very High Very High Very High
Nicotine Addiction 114 99.62 Very High Very High Very High
Malignant Neoplastic Disease 78 99.12 Very High Very High Very High
Confusion 19 97.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Combining with the cancer-miRNA network data set the obtained rules are then observed in a set of test data set.
cancer-miRNA Binding (Combining) of associated with cancer
1) Confidence 0.02 Published 2010 Journal Silenc Section Body Doc Link PMC2835996 Disease Relevance 0.57 Pain Relevance 0
Recent GWAS have identified a number of loci that appear to be associated with breast cancer susceptibility (Table 1).
susceptibility Binding (associated) of associated with breast cancer
2) Confidence 0.01 Published 2010 Journal Current Genomics Section Body Doc Link PMC2878980 Disease Relevance 0.53 Pain Relevance 0
Milder variants leading to a relative reduction of CHD7 protein has been proposed to explain its association with IS susceptibility [48].
IS susceptibility Binding (association) of associated with scoliosis
3) Confidence 0.01 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674301 Disease Relevance 0.88 Pain Relevance 0.03
Ter Meulen [31] and Moodley [28] controlled for HPV and found no association between HIV and cervical cancer.
cancer Neg (no) Binding (association) of associated with cervical cancer, genital human papilloma virus and acquired immune deficiency syndrome or hiv infection
4) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 2.56 Pain Relevance 0
Association between HIV and cancer of the cervix was established using Chi square tests and Fisher's exact test.
cancer Binding (Association) of in cervix associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
5) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 0.94 Pain Relevance 0
In logistic regression, HIV-1 was associated with cancer of the cervix (OR = 2.9, 95% CI = 1.4–5.9).
cancer Binding (associated) of in cervix associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
6) Confidence 0.01 Published 2008 Journal BMC Public Health Section Abstract Doc Link PMC2527006 Disease Relevance 2.29 Pain Relevance 0
Other risk factors such as sexually transmitted infections (STIs), age at first coitus and use of oral contraceptives were not statistically associated with cancer of the cervix.
cancer Binding (associated) of in cervix associated with cervical cancer and infection
7) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 0.90 Pain Relevance 0
Age and parity confounded the association between HIV-1 and cervical cancer, raising the odds ratio from 2.0 to 2.9.
cancer Binding (association) of associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
8) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.22 Pain Relevance 0
Notwithstanding these limitations, our study has demonstrated that HIV-1 infection is associated with invasive cancer of the cervix.
cancer Binding (associated) of in cervix associated with cervical cancer, acquired immune deficiency syndrome or hiv infection and infection
9) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.27 Pain Relevance 0
Association between invasive cancer of the cervix and HIV-1 infection in Tanzania: the need for dual screening

Background

cancer Binding (Association) of in cervix associated with cervical cancer, acquired immune deficiency syndrome or hiv infection and infection
10) Confidence 0.01 Published 2008 Journal BMC Public Health Section Title Doc Link PMC2527006 Disease Relevance 2.00 Pain Relevance 0
A review of the literature suggests that studies that have established an association between HIV and cancer of the cervix, in general, share certain characteristics.
cancer Binding (association) of in cervix associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
11) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.41 Pain Relevance 0
However, both age (OR = 1.02, 95% CI 1.00 – 1.05 per year) and parity (OR = 1.14, 95% CI 1.02–1.28 per birth) remained significantly associated with cervical cancer.
cancer Binding (associated) of associated with cervical cancer
12) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.59 Pain Relevance 0
Consistent with previous studies, smoking was significantly associated with cervical cancer but was not a confounder because it was not associated with HIV-1 infection.
cancer Binding (associated) of associated with cervical cancer, nicotine addiction, acquired immune deficiency syndrome or hiv infection and infection
13) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.79 Pain Relevance 0
Cervical cancer is associated with many risk factors including early sexual debut, having multiple sexual partners or having sex with someone who has multiple sexual partners, being HIV positive, a family history of cervical cancer, older women, smoking and poverty [7,9-11].
cancer Binding (associated) of associated with cervical cancer, nicotine addiction and acquired immune deficiency syndrome or hiv infection
14) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.66 Pain Relevance 0
Few studies have established an association between HIV and invasive cancer of the cervix in sub-Saharan Africa [1,26,27,33,34].
cancer Binding (association) of in cervix associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
15) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.95 Pain Relevance 0
The aim of the study was therefore to link the twin burdens of cervical cancer and HIV by establishing an association between invasive cancer of the cervix and HIV-1 in Tanzania.


cancer Binding (association) of in cervix associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
16) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 2.16 Pain Relevance 0.07
Our estimate for the association between HIV-1 and cervical cancer of OR = 2.9 is consistent with the risk or odds ratio range of 1.6 to 2.4 reported in previous studies.
cancer Binding (association) of associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
17) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.97 Pain Relevance 0
Smoking was significantly associated with cervical cancer (OR = 5.7, 95% CI: 1.1 – 28.9) but was not a confounder of the association between HIV-1 and cervical cancer (Table 3).


cancer Binding (association) of associated with cervical cancer, nicotine addiction and acquired immune deficiency syndrome or hiv infection
18) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 1.86 Pain Relevance 0
In sub-Saharan Africa, the situation is less clear with conflicting results on the association between HIV and invasive cervical cancer [17,25-34].
cancer Spec (clear) Binding (association) of associated with cervical cancer and acquired immune deficiency syndrome or hiv infection
19) Confidence 0.01 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2527006 Disease Relevance 2.40 Pain Relevance 0
HIV-1 infection is associated with invasive cancer of the cervix.
cancer Binding (associated) of in cervix associated with cervical cancer, acquired immune deficiency syndrome or hiv infection and infection
20) Confidence 0.01 Published 2008 Journal BMC Public Health Section Abstract Doc Link PMC2527006 Disease Relevance 1.83 Pain Relevance 0

General Comments

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