INT244415

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.57
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ctss) lysosome (Ctss)
Anatomy Link Frequency
spinal cord 1
Ctss (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 38 99.28 Very High Very High Very High
Neuropathic pain 20 97.92 Very High Very High Very High
Inflammation 6 97.88 Very High Very High Very High
Pain 20 96.52 Very High Very High Very High
bradykinin 2 95.48 Very High Very High Very High
allodynia 8 87.68 High High
Hyperalgesia 4 87.12 High High
Lasting pain 8 74.56 Quite High
medulla 4 74.00 Quite High
cytokine 2 69.40 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 34 97.92 Very High Very High Very High
INFLAMMATION 6 97.88 Very High Very High Very High
Pain 28 96.52 Very High Very High Very High
Multiple Trauma 2 92.92 High High
Gastritis 4 90.68 High High
Hyperalgesia 4 87.12 High High
Motor Neuron Diseases 2 82.68 Quite High
Disease 6 81.00 Quite High
Injury 8 52.96 Quite High
Nervous System Injury 2 29.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Extending the latter results, we were able to detect the regulation of CATS protein levels and added a new cathepsin, CATX, to the list of regulated proteases in pain pathology.
Regulation (regulation) of CATS associated with pain
1) Confidence 0.26 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2527007 Disease Relevance 0.82 Pain Relevance 0.62
Our results suggest a strong regulation of both, CATS and CATX, in the spinal cord of an animal model of neuropathic pain.
Regulation (regulation) of CATS in spinal cord associated with neuropathic pain and spinal cord
2) Confidence 0.26 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2527007 Disease Relevance 0.75 Pain Relevance 0.56

General Comments

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