INT24443

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.54
First Reported 1988
Last Reported 2010
Negated 3
Speculated 2
Reported most in Body
Documents 20
Total Number 22
Disease Relevance 7.29
Pain Relevance 2.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (PSMD2) cytosol (PSMD2) nucleoplasm (PSMD2)
small molecule metabolic process (PSMD2) cellular nitrogen compound metabolic process (PSMD2)
Anatomy Link Frequency
L14 1
PPC 1
vasculature 1
anterior 1
HeLa 1
PSMD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 19 99.84 Very High Very High Very High
Pin-prick hyperalgesia 3 99.26 Very High Very High Very High
Pain 8 98.24 Very High Very High Very High
Bile 44 95.44 Very High Very High Very High
chemokine 16 95.28 Very High Very High Very High
magnetoencephalography 3 89.96 High High
Nav1.2 3 87.44 High High
Hyperalgesia 10 83.88 Quite High
antagonist 6 83.72 Quite High
cytokine 42 80.80 Quite High
Disease Link Frequency Relevance Heat
Nervous System Malformation 1 100.00 Very High Very High Very High
Dengue Hemorrhagic Fever 205 99.80 Very High Very High Very High
Sprains And Strains 82 99.62 Very High Very High Very High
Dengue 88 99.54 Very High Very High Very High
Hyperalgesia 14 99.26 Very High Very High Very High
Systolic Murmurs 3 98.96 Very High Very High Very High
Pain 8 98.24 Very High Very High Very High
Cv Unclassified Under Development 74 97.60 Very High Very High Very High
Cardiovascular Disease 163 97.00 Very High Very High Very High
Increased Venous Pressure Under Development 11 96.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During pin-prick hyperalgesia significantly higher activation was detected in contralateral PPC and bilateral S2 but not in S1 compared to normal pin-prick pain.
Neg (not) Gene_expression (detected) of S2 in PPC associated with pain, hyperalgesia and pin-prick hyperalgesia
1) Confidence 0.54 Published 2010 Journal Eur J Pain Section Abstract Doc Link 19346142 Disease Relevance 1.23 Pain Relevance 1.38
S2-serotonergic receptors are also present in the digital vasculature and may be another important mechanism mediating digital vasoconstriction.
Gene_expression (present) of S2-serotonergic in vasculature associated with increased venous pressure under development
2) Confidence 0.41 Published 1988 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2459515 Disease Relevance 0.25 Pain Relevance 0.30
S2.It is easy to verify that s1*=defect and s2*=defect is the only NE in pure strategies for the PDG (figure 1d).
Gene_expression (=defect) of s2
3) Confidence 0.39 Published 2008 Journal Philosophical Transactions of the Royal Society B: Biological Sciences Section Body Doc Link PMC2581786 Disease Relevance 0.26 Pain Relevance 0
It allows clear detection of S1, S2 and S3 sounds, S2 split, systolic murmur, and intensity of these components.
Spec (clear) Gene_expression (detection) of S2 associated with systolic murmurs
4) Confidence 0.37 Published 2007 Journal Biomed Eng Online Section Abstract Doc Link PMC1899182 Disease Relevance 0.20 Pain Relevance 0
These probes were termed aGp (Supplementary Table S2: aGp #1–216), and the Genopal™ array performed with these probes was called an aGp array.
Gene_expression (termed) of S2
5) Confidence 0.23 Published 2010 Journal DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes Section Body Doc Link PMC2993541 Disease Relevance 1.07 Pain Relevance 0.08
U1(s1,s2*)foralls1?
Gene_expression (foralls1) of s2
6) Confidence 0.20 Published 2008 Journal Philosophical Transactions of the Royal Society B: Biological Sciences Section Body Doc Link PMC2581786 Disease Relevance 0.26 Pain Relevance 0
A 2 × 2 factorial design has been used to investigate the separate effects of the B-vitamins (S1), and the n-3 fatty acids (S2) as well as their interaction.
Spec (investigate) Gene_expression (effects) of S2
7) Confidence 0.19 Published 2008 Journal Trials Section Body Doc Link PMC2464576 Disease Relevance 0.29 Pain Relevance 0
The gene list generated at FDR10 included 2959 genes differentially expressed between DF, DHF and DSS patients groups (Table S2).
Gene_expression (groups) of S2 associated with dengue and dengue hemorrhagic fever
8) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2907396 Disease Relevance 0.64 Pain Relevance 0
and eotaxin were significantly (p<0.05) higher in D2 samples than in controls, S1, S2 and D1 samples (Figure 2).
Gene_expression (samples) of S2
9) Confidence 0.13 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2950153 Disease Relevance 0.07 Pain Relevance 0.34
The cytoplasmic RNA-binding protein UNR was originally identified as p97 in HeLa cells and lacking in RLLs.
Gene_expression (identified) of p97 in HeLa
10) Confidence 0.10 Published 2007 Journal Virol J Section Body Doc Link PMC1947962 Disease Relevance 0.35 Pain Relevance 0
Our STR analysis demonstrated that our ACC2, ACC3, and ACCM cells had nearly identical electrophoretic profiles (Table 1, and Figures 1 and S1, S2, S3, S4, S5, S6, S7, S8, S9, S10).
Gene_expression (had) of S2
11) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2698276 Disease Relevance 0.08 Pain Relevance 0
The only well defined subsites of these seven are S2, S1, and S1?
Gene_expression (subsites) of S2
12) Confidence 0.06 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2867933 Disease Relevance 0 Pain Relevance 0
, and only S2 and S1?
Gene_expression (only) of S2
13) Confidence 0.06 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2867933 Disease Relevance 0 Pain Relevance 0
-helical as proposed for S2 segments in potassium channels?
Gene_expression (segments) of S2 associated with potassium channel
14) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2766034 Disease Relevance 0 Pain Relevance 0.23
E226(S2)?
Gene_expression (E226) of S2
15) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2766034 Disease Relevance 0 Pain Relevance 0
E236(S2)?
Gene_expression (E236) of S2
16) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2766034 Disease Relevance 0 Pain Relevance 0
Power simulations are presented in Figures S1 and S2.
Gene_expression (presented) of S2
17) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.47 Pain Relevance 0
0.01 in either women or men in combined analysis of both cohorts are presented in Figure 2 and Table S2.
Gene_expression (presented) of S2
18) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.48 Pain Relevance 0
Analysis of the biological processes in the beating EBs confirms these observations, with overexpression of embryonic and organ system developmental categories including nervous system development, kidney development, skeletal muscle development, and heart development (Table S2 (A8)).


Gene_expression (overexpression) of S2 in organ system associated with nervous system malformation
19) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565131 Disease Relevance 0.16 Pain Relevance 0
Strains with the genotype s2 produce an inactive toxin.
Neg (inactive) Gene_expression (produce) of s2 associated with sprains and strains
20) Confidence 0.02 Published 2005 Journal Ann Clin Microbiol Antimicrob Section Body Doc Link PMC544872 Disease Relevance 0.71 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox