INT244467

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EIF2S2) mitochondrion (CS) small molecule metabolic process (CS)
RNA binding (EIF2S2) translation factor activity, nucleic acid binding (EIF2S2) translation (EIF2S2)
CS (Homo sapiens)
EIF2S2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 9 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 67 83.48 Quite High
Malignant Neoplastic Disease 20 50.00 Quite Low
Lung Cancer 47 48.00 Quite Low
Nicotine Addiction 30 12.92 Low Low
Cancer 40 5.00 Very Low Very Low Very Low
Hypoxia 12 5.00 Very Low Very Low Very Low
Carcinoma 12 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 9 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Small Cell Lung Cancer 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 10 also shows that treatment with reduced glutathione (GSH), a free radical scavenger that does not cross the cell membrane, also suppresses the ability of CS to induce eIF2?
Negative_regulation (suppresses) of CS Positive_regulation (induce) of eIF2
1) Confidence 0.11 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.14 Pain Relevance 0

General Comments

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