INT244468

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EIF2S2) mitochondrion (CS) small molecule metabolic process (CS)
RNA binding (EIF2S2) translation factor activity, nucleic acid binding (EIF2S2) translation (EIF2S2)
CS (Homo sapiens)
EIF2S2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 3 16.00 Low Low
Nicotine 27 5.00 Very Low Very Low Very Low
Inflammation 15 5.00 Very Low Very Low Very Low
COX-2 inhibitor 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 201 87.68 High High
Malignant Neoplastic Disease 60 74.56 Quite High
Lung Cancer 141 48.00 Quite Low
Cancer 120 25.08 Quite Low
Disease 21 24.40 Low Low
Nicotine Addiction 90 11.88 Low Low
Hypoxia 36 5.00 Very Low Very Low Very Low
Carcinoma 36 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 27 5.00 Very Low Very Low Very Low
Apoptosis 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar to the results observed with 2R4F cigarettes, CS generated from the 'full flavor' Brand A and 'lights' Brand B cigarettes also induced the rapid eIF2?
CS Positive_regulation (induced) of eIF2
1) Confidence 0.16 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.21 Pain Relevance 0
Since CS as well as thapsigargin and tunicamycin can induce eIF2?
CS Positive_regulation (induce) of eIF2
2) Confidence 0.16 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.07 Pain Relevance 0
Figure 10 also shows that treatment with reduced glutathione (GSH), a free radical scavenger that does not cross the cell membrane, also suppresses the ability of CS to induce eIF2?
CS Positive_regulation (induce) of eIF2
3) Confidence 0.12 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.14 Pain Relevance 0

General Comments

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