INT244472

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (XBP1) mitochondrion (CS) small molecule metabolic process (CS)
nucleus (XBP1) DNA binding (XBP1) carbohydrate metabolic process (CS)
CS (Homo sapiens)
XBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 18 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 60 99.00 Very High Very High Very High
Stress 134 92.92 High High
Lung Cancer 94 85.20 High High
Apoptosis 16 64.96 Quite High
Adenocarcinoma 4 51.68 Quite High
Malignant Neoplastic Disease 40 50.00 Quite Low
Cancer 80 5.00 Very Low Very Low Very Low
Hypoxia 24 5.00 Very Low Very Low Very Low
Carcinoma 24 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism by which CS suppresses XBP1 splicing is not obvious.
CS Negative_regulation (suppresses) of XBP1 Binding (splicing) of
1) Confidence 0.19 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.68 Pain Relevance 0
Another interesting observation to emerge from this study is that CS significantly suppressed the splicing of the XBP1 mRNA to its active truncated form.
CS Negative_regulation (suppressed) of XBP1 mRNA Binding (splicing) of
2) Confidence 0.16 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.39 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox