INT244476

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ATF3) mitochondrion (CS) small molecule metabolic process (CS)
nucleolus (ATF3) nucleus (ATF3) carbohydrate metabolic process (CS)
CS (Homo sapiens)
ATF3 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 1 11.32 Low Low
Nicotine 9 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 8 65.76 Quite High
Stress 67 59.40 Quite High
Malignant Neoplastic Disease 20 50.00 Quite Low
Lung Cancer 47 5.00 Very Low Very Low Very Low
Cancer 40 5.00 Very Low Very Low Very Low
Nicotine Addiction 30 5.00 Very Low Very Low Very Low
Hypoxia 12 5.00 Very Low Very Low Very Low
Carcinoma 12 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 9 5.00 Very Low Very Low Very Low
Small Cell Lung Cancer 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with this protein data, the array profiles of cigarette smoke signature genes shown in Additional file 1 – Supplemental Table S1 shows that the mRNA transcripts for CHOP (also denoted DDIT3), ATF3, and GADD34 (also denoted PPPIR15A) are upregulated by CS treatment.


CS Positive_regulation (upregulated) of ATF3
1) Confidence 0.13 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.13 Pain Relevance 0

General Comments

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