INT244495

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (HSP90B1) protein folding (HSP90B1) cytosol (HSP90B1)
endoplasmic reticulum (HSP90B1) RNA binding (HSP90B1) response to stress (HSP90B1)
Anatomy Link Frequency
Caco-2 1
HSP90B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 93.60 High High
Crohn's disease 51 91.40 High High
Inflammation 10 5.00 Very Low Very Low Very Low
Nicotine 9 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 8 98.76 Very High Very High Very High
Escherichia Infection 1 94.40 High High
Disease 62 91.40 High High
Bacterial Infection 1 87.16 High High
Necrosis 1 85.60 High High
Cancer 43 85.24 High High
Stress 84 78.36 Quite High
Sprains And Strains 27 63.04 Quite High
Inflammatory Bowel Disease 12 61.12 Quite High
Malignant Neoplastic Disease 20 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, when the array data was assessed to determine changes in the levels of three genes whose transcription is dependent on activated ATF6 (i.e., BiP, XBP1, and grp94) [60], we found that both XBP1 and BiP transcript levels are elevated in response to CS treatment (Figure 5).
Transcription (transcription) of grp94
1) Confidence 0.28 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.15 Pain Relevance 0
No modification in gp96 mRNA levels was observed in Caco-2 cells after TNF?
Transcription (levels) of gp96 in Caco-2
2) Confidence 0.23 Published 2010 Journal Gut Section Body Doc Link PMC2976078 Disease Relevance 1.31 Pain Relevance 0.40

General Comments

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