INT244554

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PPP1R15A) response to stress (PPP1R15A)
PPP1R15A (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 1 21.72 Low Low
cytokine 42 5.00 Very Low Very Low Very Low
imagery 27 5.00 Very Low Very Low Very Low
Central nervous system 21 5.00 Very Low Very Low Very Low
Inflammation 17 5.00 Very Low Very Low Very Low
Pain 16 5.00 Very Low Very Low Very Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
Nerve growth factor 10 5.00 Very Low Very Low Very Low
Nicotine 9 5.00 Very Low Very Low Very Low
Peripheral nervous system 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 367 91.56 High High
Cancer 242 85.48 High High
Glioma 11 85.20 High High
Apoptosis 38 76.16 Quite High
Viral Infection 9 72.64 Quite High
Stress 68 69.80 Quite High
Malignant Neoplastic Disease 23 50.00 Quite Low
Infection 67 49.76 Quite Low
Cholangiocarcinoma 2 9.16 Low Low
Lung Cancer 48 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ATF3-induced expression has a similar time-course as ATF4 (i.e., peaking around 4 hrs post-exposure) while peak GADD34 expression occurs between 7–12 hrs post-exposure.
Gene_expression (expression) of GADD34
1) Confidence 0.24 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.20 Pain Relevance 0
Cisplatin significantly increased viral titer and resulted in a marked increase in GADD34 mRNA and protein expression.



Gene_expression (expression) of GADD34
2) Confidence 0.15 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 0.98 Pain Relevance 0

General Comments

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