INT244683

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.78
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Mmp2) cytoplasm (Mmp2) extracellular space (Mmp2)
peptidase activity (Mmp2) extracellular region (Mmp2) proteinaceous extracellular matrix (Mmp2)
Mmp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 51 87.60 High High
dexamethasone 9 68.16 Quite High
fibrosis 31 62.48 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 21 88.72 High High
Hyperoxia 7 69.28 Quite High
Cirrhosis 30 63.72 Quite High
Injury 10 63.48 Quite High
Metabolic Disorder 1 52.52 Quite High
Gallstones 1 51.52 Quite High
Viral Infection 1 51.00 Quite High
Bronchopulmonary Dysplasia 61 50.80 Quite High
Liver Disease 1 49.72 Quite Low
Genetic Predisposition To Disease 3 46.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The functional domains of MMP16 and MMP14 are not interchangeable for pro-MMP2 activation and collagenolysis, despite their similarities [28].
Neg (not) Regulation (interchangeable) of Positive_regulation (activation) of MMP2
1) Confidence 0.36 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527515 Disease Relevance 0.12 Pain Relevance 0.03
The mechanism of activation involves TIMP-2 interaction with MT1-MMP to form a receptor complex that regulates the activation of MMP-2 (8-11).
Regulation (regulates) of Positive_regulation (activation) of MMP-2
2) Confidence 0.13 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2844613 Disease Relevance 0.66 Pain Relevance 0.40

General Comments

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