INT244773

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.13
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hoxd10) DNA binding (Hoxd10)
Anatomy Link Frequency
neural tube 1
band 1
Hoxd10 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 2 91.80 High High
Pain 1 72.16 Quite High
substantia gelatinosa 2 49.36 Quite Low
imagery 12 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
Dorsal horn neuron 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 1 72.16 Quite High
Targeted Disruption 46 60.16 Quite High
Disseminated Intravascular Coagulation 8 5.00 Very Low Very Low Very Low
Wound Healing 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Calcification 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Strong expression was also indicated for two of the paralogous genes, Hoxa11 and Hoxd10, whereas no RT-PCR amplification product was detected for Hoxa10, and the band corresponding to Hoxd11 was weak (Fig. 4A).
Gene_expression (expression) of Hoxd10 in band
1) Confidence 0.50 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570687 Disease Relevance 0 Pain Relevance 0
In addition to examining this RNA sample for the presence of Hoxc11-specific transcripts, we determined whether there was evidence for expression of the remaining AbdB-type Hoxc genes (Hoxc9, Hoxc10, Hoxc12, and Hoxc13), as well as for the Hoxc11 and Hoxc10 paralogous genes (Hoxa11, Hoxd11, and Hoxa10, Hoxd10).
Gene_expression (expression) of Hoxd10
2) Confidence 0.28 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570687 Disease Relevance 0.06 Pain Relevance 0
It is also known that Hoxc6, c8, c9, d9, and d10 gene expression is restricted to postmitotic cells in the ventral region of the neural tube at E12.5 [40]–[43].
Gene_expression (expression) of d10 in neural tube
3) Confidence 0.10 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.07 Pain Relevance 0.12

General Comments

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