INT244853

Context Info Confidence 0.41 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

nucleus (Lbx1, Satb2) DNA binding (Lbx1, Satb2) cell differentiation (Lbx1) cytoplasm (Satb2)

Anatomy Link Frequency neural tube 1 Lbx1 (Mus musculus) Satb2 (Mus musculus)

Pain Link Frequency Relevance Heat substantia gelatinosa 2 39.76 Spinal cord 2 5.00 Dorsal horn neuron 1 5.00 Central nervous system 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 6 5.00 Apoptosis 2 5.00 Pain 1 5.00 Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Five target genes (Pax2, Lmx1b, Lhx1/5, Satb2, Gbx1) are known to be activated by Lbx1 in the developing neural tube [9], [30], [34], [35].

Lbx1 Positive_regulation (activated) of Satb2 in neural tube

1) Confidence 0.41 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.