INT244922

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SPTBN1) nucleolus (SPTBN1) plasma membrane (SPTBN1)
nucleus (SPTBN1) cytoplasm (SPTBN1)
Anatomy Link Frequency
lenses 2
SPTBN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 62.04 Quite High
Kinase C 6 52.64 Quite High
Dopamine 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperopia 18 53.76 Quite High
Disorder Of Lipid Metabolism 2 50.28 Quite High
Myopia 44 50.00 Quite Low
Sarcoma 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 2 5.00 Very Low Very Low Very Low
Refractive Errors 2 5.00 Very Low Very Low Very Low
Thymoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first cluster includes genes that showed changes in the same directions, no matter whether positive or negative lenses were used: “image sharpness detection” (ATE1, ELF1, GRB2, SHQ1, SPTBN1, and pp-URP).
Transcription (detection) of SPTBN1 in lenses
1) Confidence 0.39 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2528026 Disease Relevance 0 Pain Relevance 0
Since SPTBN1 mRNA expression was generally upregulated in both the positive- and the negative lens-treated group, we propose a more general role of this protein in retinal processing.


Transcription (expression) of SPTBN1 in lens
2) Confidence 0.30 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2528026 Disease Relevance 0.10 Pain Relevance 0.06

General Comments

This test has worked.

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