INT244935

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 10
Disease Relevance 4.77
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (St13) protein folding (St13) cytosol (St13)
protein complex (St13) cytoplasm (St13)
Anatomy Link Frequency
hip 6
knee 2
spine 1
wrist 1
St13 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Osteoarthritis 20 98.88 Very High Very High Very High
Lasting pain 5 96.96 Very High Very High Very High
Pain 5 78.20 Quite High
Arthritis 5 76.76 Quite High
alcohol 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frailty 525 100.00 Very High Very High Very High
Death 15 99.40 Very High Very High Very High
Injury 15 99.00 Very High Very High Very High
Osteoporosis 35 98.60 Very High Very High Very High
Disease 15 97.12 Very High Very High Very High
Pain 10 96.96 Very High Very High Very High
Hip Fractures 155 90.12 High High
Arthritis 5 76.76 Quite High
Osteoporotic Fractures 10 27.36 Quite Low
Nicotine Addiction 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Osteoporotic hip fracture is an established health problem in the West and is increasingly recognized as a growing problem in Asia as per the Asian Audit Report, 2009.1 With rising life expectancy throughout the globe, the number of elderly individuals is increasing in every geographical region, and it is estimated that the incidence of hip fracture will rise from 1.66 million in 1990 to 6.26 million by 2050.2
hip Binding (recognized) of in hip associated with frailty
1) Confidence 0.35 Published 2011 Journal Indian Journal of Orthopaedics Section Body Doc Link PMC3004072 Disease Relevance 0.93 Pain Relevance 0.10
Hip fracture has been recognized as the most serious consequence of osteoporosis because of its complications, which include chronic pain, disability, diminished quality of life, and premature death.
Hip Binding (recognized) of in Hip associated with lasting pain, frailty, osteoporosis and death
2) Confidence 0.35 Published 2011 Journal Indian Journal of Orthopaedics Section Body Doc Link PMC3004072 Disease Relevance 0.73 Pain Relevance 0.10
Epidemiology of hip fracture: Worldwide geographic variation

Osteoporosis is a major health problem, especially in elderly populations, and is associated with fragility fractures at the hip, spine, and wrist.

hip Binding (associated) of in wrist associated with frailty and osteoporosis
3) Confidence 0.26 Published 2011 Journal Indian Journal of Orthopaedics Section Title Doc Link PMC3004072 Disease Relevance 0.69 Pain Relevance 0
Post hip replacement, the highest revision rate was in patients who had undergone hip resurfacing, especially women.
hip Binding (replacement) of in hip
4) Confidence 0.13 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2528048 Disease Relevance 0.17 Pain Relevance 0.04
Women were found to have higher revision rates after hip resurfacing, and the revision rate was about twice as high in patients who had had a hip replacement for other indications than osteoarthritis.
hip Binding (replacement) of in hip associated with osteoarthritis
5) Confidence 0.13 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2528048 Disease Relevance 0.16 Pain Relevance 0.05
To date, little evidence has been available to compare patient outcomes following hip or knee replacement with the many different types of techniques and prostheses available.
hip Binding (replacement) of in knee
6) Confidence 0.13 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2528048 Disease Relevance 0.22 Pain Relevance 0.10
The techniques for hip and knee replacement can also be divided into those where a cement is used to position the metal implant into the bone (cemented) versus those where cement is not used (cementless).


hip Binding (replacement) of in hip
7) Confidence 0.13 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2528048 Disease Relevance 0.25 Pain Relevance 0.12
Epidemiology of hip fracture: Worldwide geographic variation

Osteoporosis is a major health problem, especially in elderly populations, and is associated with fragility fractures at the hip, spine, and wrist.

hip Binding (associated) of in hip associated with frailty and osteoporosis
8) Confidence 0.09 Published 2011 Journal Indian Journal of Orthopaedics Section Title Doc Link PMC3004072 Disease Relevance 0.69 Pain Relevance 0
Epidemiology of hip fracture: Worldwide geographic variation

Osteoporosis is a major health problem, especially in elderly populations, and is associated with fragility fractures at the hip, spine, and wrist.

hip Binding (associated) of in spine associated with frailty and osteoporosis
9) Confidence 0.09 Published 2011 Journal Indian Journal of Orthopaedics Section Title Doc Link PMC3004072 Disease Relevance 0.69 Pain Relevance 0
The techniques for hip and knee replacement can also be divided into those where a cement is used to position the metal implant into the bone (cemented) versus those where cement is not used (cementless).


hip Binding (replacement) of in knee
10) Confidence 0.04 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2528048 Disease Relevance 0.25 Pain Relevance 0.12

General Comments

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