INT245025

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 1.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Xrcc1) intracellular (Xrcc1)
Anatomy Link Frequency
neuronal 2
SH-SY5Y 2
Xrcc1 (Mus musculus)
Pain Link Frequency Relevance Heat
bDMF 5 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 20 99.46 Very High Very High Very High
Rheumatoid Arthritis 55 98.54 Very High Very High Very High
Infection 20 97.64 Very High Very High Very High
Stress 85 91.60 High High
Hypersensitivity 15 80.68 Quite High
Apoptosis 80 71.68 Quite High
Targeted Disruption 5 70.64 Quite High
Ataxia 25 5.00 Very Low Very Low Very Low
Spinocerebellar Ataxia Type 2 15 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We point out that the nondividing XKD cells were down-regulated significantly for XRCC1 protein expression and exhibited ?
Regulation (regulated) of Gene_expression (expression) of XRCC1
1) Confidence 0.45 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.28 Pain Relevance 0
Figure 1B shows the expression of XRCC1 protein in the control (scramble) and XRCC1-knockdown (XKD) shRNA replicating cells.
Regulation (control) of Gene_expression (expression) of XRCC1
2) Confidence 0.45 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.16 Pain Relevance 0
Finally, we note that Narciso et al. (33) recently reported down-regulation of XRCC1 in differentiated human skeletal muscle cells; however, analysis of expressional changes of several DNA damage response genes following RA-BDNF differentiation of SH-SY5Y neuroblastoma cells did not reveal down-regulation of XRCC1 protein expression (Kulkarni and Wilson, unpublished observations), suggesting a cell type-specific regulation of this gene product.
Regulation (regulation) of Gene_expression (expression) of XRCC1 in SH-SY5Y associated with neuroblastoma and rheumatoid arthritis
3) Confidence 0.45 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.41 Pain Relevance 0
Figure 1B shows the expression of XRCC1 protein in the control (scramble) and XRCC1-knockdown (XKD) shRNA replicating cells.
Regulation (control) of Gene_expression (expression) of XRCC1
4) Confidence 0.45 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.15 Pain Relevance 0
Effect of XRCC1 deficiency on primary mouse and human neuronal cell survival
Regulation (Effect) of Gene_expression (deficiency) of XRCC1 in neuronal
5) Confidence 0.45 Published 2008 Journal Nucleic Acids Research Section Body Doc Link PMC2528184 Disease Relevance 0.44 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox