INT245109

Context Info Confidence 0.12 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.14 Pain Relevance 0

cytoplasm (MMP14)

MMP14 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 2 50.00 palliative 1 5.00

Disease Link Frequency Relevance Heat Cancer 19 94.08 Prostate Cancer 35 86.76 Osteolysis 4 79.56 Metastasis 23 58.96 Malignant Neoplastic Disease 1 35.08 Aggression 1 27.92 Congenital Anomalies 2 19.76 Targeted Disruption 1 17.84 Pathologic Processes 1 15.44 Osteoporosis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

That effect was abrogated by pharmacologic inhibition of mt1-mmp activity and by osteoprotegerin, a soluble decoy receptor of the osteoclastogenic receptor activator of nuclear factor ?

Negative_regulation (inhibition) of mt1-mmp Binding (activity) of

1) Confidence 0.12 Published 2008 Journal Current Oncology Section Body Doc Link PMC2528310 Disease Relevance 1.14 Pain Relevance 0

General Comments

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