INT245118

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.41
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (RBM45, CDKN2B) cytoplasm (RBM45, CDKN2B) cytosol (CDKN2B)
cell differentiation (RBM45) RNA binding (RBM45) kinase activity (CDKN2B)
RBM45 (Homo sapiens)
CDKN2B (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 75.76 Quite High
shoulder pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 18 99.66 Very High Very High Very High
Lung Cancer 7 98.72 Very High Very High Very High
Metastasis 4 94.88 High High
Hemoptysis 1 79.76 Quite High
Pain 1 75.76 Quite High
Skin Cancer 12 68.32 Quite High
Carcinoma 1 39.28 Quite Low
Nicotine Addiction 1 22.76 Low Low
Hodgkin's Disease 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Loss of tumor suppressor gene RB, inactivation of CDK-inhibitor, and overexpression of epidermal growth-factor receptor might contribute to the development of neoplasm.
RB Negative_regulation (inactivation) of CDK-inhibitor associated with cancer
1) Confidence 0.01 Published 2008 Journal Cases J Section Body Doc Link PMC2529260 Disease Relevance 1.41 Pain Relevance 0.08

General Comments

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