INT245218

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.94
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (C3, C5AR1) extracellular space (C3) extracellular region (C3)
plasma membrane (C5AR1) signal transducer activity (C5AR1)
Anatomy Link Frequency
cleavage 1
C3 (Homo sapiens)
C5AR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 14 84.64 Quite High
tolerance 1 18.72 Low Low
Inflammation 6 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 39 98.68 Very High Very High Very High
Dengue 104 97.28 Very High Very High Very High
Infection 38 97.00 Very High Very High Very High
Flavivirus Infection 80 95.16 Very High Very High Very High
Peripheral Arterial Disease 54 93.92 High High
Cerebrovascular Disease 1 92.60 High High
Cardiovascular Disease 2 91.60 High High
Disease 34 88.36 High High
INFLAMMATION 20 84.24 Quite High
Targeted Disruption 1 23.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also measured the plasma levels of C3a, a product of C3 cleavage, and C5a, a product of C5 cleavage, in samples from patients with confirmed dengue infection and different clinical diagnoses (Figure 2).
C3 Binding (cleavage) of C5a in cleavage associated with dengue and infection
1) Confidence 0.29 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2728508 Disease Relevance 1.73 Pain Relevance 0
For example, C3AR1 and C5R1 are receptors of C3 (C3a) and C5a respectively.
C3 Binding (receptors) of C5R1
2) Confidence 0.19 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2529314 Disease Relevance 1.21 Pain Relevance 0.04

General Comments

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