INT245313

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MMP2, TIMP1) peptidase activity (MMP2) extracellular space (MMP2)
aging (TIMP1) proteinaceous extracellular matrix (MMP2) plasma membrane (MMP2)
Anatomy Link Frequency
cartilage 2
MMP2 (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 45 98.92 Very High Very High Very High
Potency 2 43.32 Quite Low
Pain 5 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 46 98.92 Very High Very High Very High
Arthritis 5 82.72 Quite High
Injury 1 78.28 Quite High
Pain 5 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
None of the commercial chondroprotective drugs are reported to inhibit hyaluronidase; whereas the drugs nimusulide (23) and doxycycline (24) inhibit activities of collagenase and gelatinase in cartilage derived from osteoarthritis patients in vitro.
Negative_regulation (inhibit) of gelatinase Binding (activities) of collagenase in cartilage associated with osteoarthritis
1) Confidence 0.01 Published 2008 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2529383 Disease Relevance 0.45 Pain Relevance 0.11

General Comments

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