INT245316

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ADI1) Golgi apparatus (ADI1) cytoplasm (ADI1)
cytosol (ADI1) oxidoreductase activity (ADI1) nucleolus (ADI1)
Anatomy Link Frequency
chondrocytes 1
ADI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 45 98.72 Very High Very High Very High
Potency 2 79.80 Quite High
Arthritis 2 61.52 Quite High
Pain 5 51.76 Quite High
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 46 98.72 Very High Very High Very High
Arthritis 5 61.52 Quite High
Pain 5 51.76 Quite High
Disease 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One in vitro study also showed that chondrocytes from 40% of OA cases did not show increased aggrecan core protein levels, and decreased levels of MMP-protein in response to GS treatment (18).
Negative_regulation (decreased) of MMP-protein in chondrocytes associated with osteoarthritis
1) Confidence 0.01 Published 2008 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2529383 Disease Relevance 0.77 Pain Relevance 0.45

General Comments

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