INT245352

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 2.70
Pain Relevance 2.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (ARSG) sulfur compound metabolic process (ARSG) endoplasmic reticulum (ARSG)
lysosome (ARSG)
Anatomy Link Frequency
frontal cortex 3
occipital cortex 1
striatum 1
thalamus 1
hippocampus 1
ARSG (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 104 98.40 Very High Very High Very High
Thalamus 32 96.72 Very High Very High Very High
Hippocampus 40 96.16 Very High Very High Very High
antagonist 16 94.24 High High
positron emission tomography 304 86.12 High High
imagery 56 70.28 Quite High
Glutamate 8 46.88 Quite Low
nMDA receptor 32 40.96 Quite Low
Nicotine 24 5.00 Very Low Very Low Very Low
anesthesia 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 72 99.68 Very High Very High Very High
Schizophrenia 120 90.20 High High
Disease 128 61.64 Quite High
Depression 8 5.00 Very Low Very Low Very Low
Drug Dependence 8 5.00 Very Low Very Low Very Low
Anxiety Disorder 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, subchronic administration of PCP decreased the binding of [11C]CHIBA-1001 in several regions (frontal cortex, temporal cortex, occipital cortex, striatum, thalamus, and hippocampus) of the monkey brain; the difference of binding in the frontal cortex was statistically significant (t?
CHIBA-1001 Binding (binding) of in frontal cortex associated with urological neuroanatomy, hippocampus and thalamus
1) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.36 Pain Relevance 0.27
Third, we found a reduction of [11C]CHIBA-1001 binding in the frontal cortex of the monkey brain after subchronic administration of PCP.
CHIBA-1001 Binding (binding) of in frontal cortex associated with urological neuroanatomy
2) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.18 Pain Relevance 0.23
Interestingly, the binding of [11C]CHIBA-1001 in the frontal cortex of the monkey brain was significantly decreased by subchronic administration of the N-methyl-D-aspartate (NMDA) receptor antagonist phencyclidine (0.3 mg/kg, twice a day for 13 days); which is a non-human primate model of schizophrenia.


CHIBA-1001 Binding (binding) of in frontal cortex associated with antagonist, urological neuroanatomy and schizophrenia
3) Confidence 0.01 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2529405 Disease Relevance 0.37 Pain Relevance 0.35
Interestingly, subchronic administration of PCP decreased the binding of [11C]CHIBA-1001 in several regions (frontal cortex, temporal cortex, occipital cortex, striatum, thalamus, and hippocampus) of the monkey brain; the difference of binding in the frontal cortex was statistically significant (t?
CHIBA-1001 Binding (binding) of in striatum associated with urological neuroanatomy, hippocampus and thalamus
4) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.36 Pain Relevance 0.27
Interestingly, subchronic administration of PCP decreased the binding of [11C]CHIBA-1001 in several regions (frontal cortex, temporal cortex, occipital cortex, striatum, thalamus, and hippocampus) of the monkey brain; the difference of binding in the frontal cortex was statistically significant (t?
CHIBA-1001 Binding (binding) of in thalamus associated with urological neuroanatomy, hippocampus and thalamus
5) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.36 Pain Relevance 0.27
Interestingly, subchronic administration of PCP decreased the binding of [11C]CHIBA-1001 in several regions (frontal cortex, temporal cortex, occipital cortex, striatum, thalamus, and hippocampus) of the monkey brain; the difference of binding in the frontal cortex was statistically significant (t?
CHIBA-1001 Binding (binding) of in temporal cortex associated with urological neuroanatomy, hippocampus and thalamus
6) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.36 Pain Relevance 0.27
Interestingly, subchronic administration of PCP decreased the binding of [11C]CHIBA-1001 in several regions (frontal cortex, temporal cortex, occipital cortex, striatum, thalamus, and hippocampus) of the monkey brain; the difference of binding in the frontal cortex was statistically significant (t?
CHIBA-1001 Binding (binding) of in hippocampus associated with urological neuroanatomy, hippocampus and thalamus
7) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.36 Pain Relevance 0.27
Interestingly, subchronic administration of PCP decreased the binding of [11C]CHIBA-1001 in several regions (frontal cortex, temporal cortex, occipital cortex, striatum, thalamus, and hippocampus) of the monkey brain; the difference of binding in the frontal cortex was statistically significant (t?
CHIBA-1001 Binding (binding) of in occipital cortex associated with urological neuroanatomy, hippocampus and thalamus
8) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2529405 Disease Relevance 0.36 Pain Relevance 0.27

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