INT245527

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Runx3) DNA binding (Runx3) cytoplasm (Runx3)
Anatomy Link Frequency
sensory neurons 2
Runx3 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 55 88.24 High High
Dorsal horn 1 60.96 Quite High
Spinal cord 10 55.96 Quite High
nociceptor 1 38.44 Quite Low
Neuropeptide 2 28.92 Quite Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
trigeminal ganglion 1 5.00 Very Low Very Low Very Low
Root ganglion neuron 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 58 88.24 High High
Nociception 12 72.36 Quite High
Targeted Disruption 17 64.56 Quite High
Repression 3 23.16 Low Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Hematological Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Microarray studies have shown decreased levels of Runx1 and Runx3 transcripts in the sensory neurons of Brn-3a-knokout mice [40,41].
Negative_regulation (decreased) of Transcription (levels) of Runx3 in sensory neurons
1) Confidence 0.42 Published 2008 Journal Neural Develop Section Body Doc Link PMC2531103 Disease Relevance 0.59 Pain Relevance 0.17

General Comments

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