INT245565

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Runx1, Cdkn1a) cytosol (Cdkn1a) cell cycle (Cdkn1a)
DNA binding (Runx1) kinase activity (Cdkn1a) transcription factor binding (Runx1)
Runx1 (Mus musculus)
Cdkn1a (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 55 98.88 Very High Very High Very High
trigeminal ganglion 1 71.44 Quite High
Spinal cord 10 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Dorsal horn 1 5.00 Very Low Very Low Very Low
Root ganglion neuron 1 5.00 Very Low Very Low Very Low
nociceptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 3 100.00 Very High Very High Very High
Ganglion Cysts 58 98.88 Very High Very High Very High
Neurodegenerative Disease 4 93.96 High High
Targeted Disruption 17 80.52 Quite High
Osteoporosis 1 67.80 Quite High
Sprains And Strains 2 62.40 Quite High
Nociception 12 60.28 Quite High
Death 2 57.28 Quite High
Starvation 1 56.24 Quite High
Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Runx1 drives the cell cycle in ORN progenitors through transcription repression of the cyclin dependent kinase inhibitor p21 [23].
Runx1 Negative_regulation (repression) of Negative_regulation (repression) of p21 associated with repression
1) Confidence 0.29 Published 2008 Journal Neural Develop Section Body Doc Link PMC2531103 Disease Relevance 1.17 Pain Relevance 0.23

General Comments

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