INT245566

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) plasma membrane (Ntrk1) nucleus (Runx1)
DNA binding (Runx1) kinase activity (Ntrk1) transcription factor binding (Runx1)
Runx1 (Mus musculus)
Ntrk1 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 55 85.92 High High
Spinal cord 10 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
trigeminal ganglion 1 5.00 Very Low Very Low Very Low
Dorsal horn 1 5.00 Very Low Very Low Very Low
Root ganglion neuron 1 5.00 Very Low Very Low Very Low
nociceptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 58 85.92 High High
Nociception 12 77.68 Quite High
Targeted Disruption 17 76.84 Quite High
Osteoporosis 1 62.56 Quite High
Repression 3 59.32 Quite High
Neurodegenerative Disease 4 10.88 Low Low
Cancer 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, two putative target genes that are repressed by Runx1, trkA and CGRP, were unaffected in the delta446 mice [53].
Runx1 Negative_regulation (repressed) of trkA
1) Confidence 0.39 Published 2008 Journal Neural Develop Section Body Doc Link PMC2531103 Disease Relevance 0.65 Pain Relevance 0.15

General Comments

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