INT245569

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Runx3, Gtf3a) DNA binding (Runx3, Gtf3a) RNA binding (Gtf3a)
intracellular (Gtf3a) cytoplasm (Runx3)
Anatomy Link Frequency
sensory neurons 1
Runx3 (Mus musculus)
Gtf3a (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 55 80.72 Quite High
Dorsal horn 1 67.36 Quite High
Spinal cord 10 62.36 Quite High
nociceptor 1 44.84 Quite Low
Neuropeptide 2 35.32 Quite Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
trigeminal ganglion 1 5.00 Very Low Very Low Very Low
Root ganglion neuron 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 58 80.72 Quite High
Nociception 12 78.76 Quite High
Targeted Disruption 17 70.96 Quite High
Repression 3 29.56 Quite Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Hematological Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both Runx3 and Runx1 genes contain Brn-3a binding sites in their 5'-upstream regions, suggesting that Runx3 and Runx1 are candidate downstream targets of Brn-3a, a well characterized transcription factor in sensory neurons [38,39].
Runx3 Regulation (targets) of factor in sensory neurons
1) Confidence 0.01 Published 2008 Journal Neural Develop Section Body Doc Link PMC2531103 Disease Relevance 0.65 Pain Relevance 0.16

General Comments

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