INT245588

Context Info Confidence 0.05 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.81 Pain Relevance 0.17

transferase activity, transferring glycosyl groups (B3galt6) Golgi apparatus (B3galt6)

Anatomy Link Frequency brain 4 B3galt6 (Mus musculus)

Pain Link Frequency Relevance Heat Hippocampus 24 87.84 midbrain 4 84.40 Thalamus 16 5.00 cerebral cortex 10 5.00 Eae 8 5.00 Pyramidal cell 6 5.00 Spinal cord 4 5.00 sodium channel 4 5.00 Central nervous system 2 5.00 amygdala 2 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 88 100.00 Volume Depletion And Dehydration 2 88.60 Overdose 4 52.28 Cognitive Disorder 20 5.00 Anxiety Disorder 16 5.00 Body Weight 4 5.00 Nociception 4 5.00 Pain 2 5.00 Apoptosis 2 5.00 Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Semiquantitative RT-PCR for PTPH1 and beta-gal gene expression was performed in different brain areas of PTPH1-KO and WT mice in order to confirm the presence of beta-gal expression in the KO tissues, replacing PTPH1 PDZ and catalytic domain.

Regulation (presence) of Gene_expression (expression) of beta-gal in brain associated with targeted disruption

1) Confidence 0.05 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2531118 Disease Relevance 0.38 Pain Relevance 0.09

Semiquantitative RT-PCR for PTPH1 and beta-gal gene expression was performed in different brain areas of PTPH1-KO and WT mice in order to confirm the presence of beta-gal expression in the KO tissues, replacing PTPH1 PDZ and catalytic domain.

Regulation (presence) of Gene_expression (expression) of beta-gal in brain associated with targeted disruption

2) Confidence 0.05 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2531118 Disease Relevance 0.43 Pain Relevance 0.08

General Comments

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