INT2457

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Context Info
Confidence 0.59
First Reported 1979
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.20
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Agt, Avp) extracellular region (Agt, Avp) signal transduction (Avp)
aging (Agt) extracellular matrix organization (Agt) response to stress (Avp)
Agt (Rattus norvegicus)
Avp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 3 99.18 Very High Very High Very High
Enkephalin 10 99.08 Very High Very High Very High
opiate 3 93.60 High High
antagonist 3 78.44 Quite High
Nicotine 2 70.52 Quite High
tetrodotoxin 2 70.12 Quite High
Action potential 2 66.16 Quite High
narcan 2 54.32 Quite High
Endogenous opioid 1 49.44 Quite Low
Disease Link Frequency Relevance Heat
Volume Depletion And Dehydration 2 99.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of intracerebroventricular (i.c.v.) injection of leumorphin on the vasopressin secretion induced by angiotensin II or dehydration were studied in conscious unrestrained rats.
angiotensin II Positive_regulation (induced) of Localization (secretion) of vasopressin associated with volume depletion and dehydration and intracerebroventricular
1) Confidence 0.59 Published 1986 Journal NIDA Res. Monogr. Section Abstract Doc Link 3123947 Disease Relevance 0.10 Pain Relevance 0.05
The vasopressin secretion induced by angiotensin II (100 pmol) was significantly inhibited by the simultaneous injection of leumorphin (6 pmol-600 pmol) in a dose-dependent manner.
angiotensin II Positive_regulation (induced) of Localization (secretion) of vasopressin
2) Confidence 0.43 Published 1986 Journal NIDA Res. Monogr. Section Abstract Doc Link 3123947 Disease Relevance 0.10 Pain Relevance 0.05
It is concluded that angiotensin stimulates release of vasopressin by interaction with specific, saralasin-sensitive, receptors; leucine5-enkephalin inhibits angiotensin release of vasopressin; and an endogenously synthesized opiate ligand(s) may affect angiotensin drinking behavior.
angiotensin Positive_regulation (stimulates) of Localization (release) of vasopressin associated with opiate and enkephalin
3) Confidence 0.35 Published 1981 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7229996 Disease Relevance 0 Pain Relevance 0.71
Angiotensin II (AII) stimulated vasopressin (VP) release from the rat hypothalamo-neurohypophyseal system (HNS) in organ culture in a concentration-dependent manner.
Angiotensin II Positive_regulation (stimulated) of Localization (release) of vasopressin
4) Confidence 0.15 Published 1979 Journal Endocrinology Section Abstract Doc Link 446341 Disease Relevance 0 Pain Relevance 0.11
Angiotensin stimulation of vasopressin release from the rat hypothalamo-neurohypophyseal system in organ culture.
Angiotensin Positive_regulation (stimulation) of Localization (release) of vasopressin
5) Confidence 0.14 Published 1979 Journal Endocrinology Section Title Doc Link 446341 Disease Relevance 0 Pain Relevance 0.18

General Comments

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