INT245735

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (SOX9) extracellular region (COL5A2) nucleolus (SOX9)
nucleus (SOX9) molecular_function (COL5A2) extracellular matrix organization (SOX9)
Anatomy Link Frequency
cartilage 1
SOX9 (Homo sapiens)
COL5A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
backache 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Sciatica 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 33 83.00 Quite High
Intervertebral Disk Degeneration 39 77.32 Quite High
Aging 1 43.20 Quite Low
Low Back Pain 4 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Nicotine Addiction 3 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Spinal Osteophytosis 2 5.00 Very Low Very Low Very Low
Scheuermann's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sox9 has been shown to regulate the genes encoding aggrecan 31 and type XI collagen 32, and may also regulate other structural and/or patterning gene involved in cartilage and bone development 33.
Sox9 Regulation (regulate) of collagen in cartilage
1) Confidence 0.07 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.29 Pain Relevance 0

General Comments

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