INT245765

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.87
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (SOX9) nucleolus (SOX9) nucleus (SOX9)
extracellular matrix organization (SOX9) protein complex assembly (SOX9) protein complex (SOX9)
Anatomy Link Frequency
intervertebral disc 2
SOX9 (Homo sapiens)
Pain Link Frequency Relevance Heat
backache 8 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Sciatica 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 66 100.00 Very High Very High Very High
Intervertebral Disk Degeneration 78 99.16 Very High Very High Very High
Aging 2 92.56 High High
Spinal Osteophytosis 4 33.28 Quite Low
Obesity 4 23.08 Low Low
Scheuermann's Disease 2 5.56 Low Low
Low Back Pain 8 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Nicotine Addiction 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutation and polymorphism of Sox9 gene and association with intervertebral disc degeneration remain to be studied.

4.5 Vitamin D receptor

Sox9 Binding (association) of in intervertebral disc associated with intervertebral disk degeneration
1) Confidence 0.31 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.47 Pain Relevance 0
To date, there are no known associations of polymorphisms in collagen type IV and/or collagen type X genes, with intervertebral disc disease.

4.4 Sox9

Sox9 Binding (intervertebral) of in intervertebral disc associated with disease
2) Confidence 0.31 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.40 Pain Relevance 0

General Comments

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