INT245798

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.90
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ocln) plasma membrane (Ocln) cytoplasm (Ocln)
Ocln (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 27 99.86 Very High Very High Very High
ischemia 8 98.44 Very High Very High Very High
imagery 3 39.60 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
Neurobehavioral 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 162 99.84 Very High Very High Very High
Cv Unclassified Under Development 4 98.44 Very High Very High Very High
Targeted Disruption 2 90.64 High High
Injury 14 84.96 Quite High
Diabetic Retinopathy 6 73.76 Quite High
Pressure And Volume Under Development 9 71.68 Quite High
Brain Hemorrhage 20 68.32 Quite High
Diabetic Macular Edema 11 63.28 Quite High
Hematoma 4 62.32 Quite High
Retinal Neovascularization 1 60.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the current study, MMP-9 was increased in microvessel preparation along with decreased occludin.
Positive_regulation (increased) of Negative_regulation (decreased) of occludin associated with metalloproteinase
1) Confidence 0.27 Published 2010 Journal Diabetes Section Body Doc Link PMC2797926 Disease Relevance 1.01 Pain Relevance 0.19
This effect is associated with downregulation of retinal VEGF and phospho-p42/p44 MAP kinase expression, and a reduction in the retinal occludin loss induced by diabetes.
Positive_regulation (induced) of Negative_regulation (loss) of occludin associated with diabetes mellitus
2) Confidence 0.11 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2533034 Disease Relevance 0.89 Pain Relevance 0.03

General Comments

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