INT245799

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Context Info
Confidence 0.62
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.78
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ocln) plasma membrane (Ocln) cytoplasm (Ocln)
Ocln (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 27 99.56 Very High Very High Very High
ischemia 8 99.08 Very High Very High Very High
imagery 3 28.72 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
Neurobehavioral 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 4 99.08 Very High Very High Very High
Diabetes Mellitus 162 97.56 Very High Very High Very High
Increased Venous Pressure Under Development 2 83.96 Quite High
Diabetic Macular Edema 11 82.52 Quite High
Diabetic Retinopathy 6 77.48 Quite High
Hypoxia 3 67.24 Quite High
Pressure And Volume Under Development 9 60.80 Quite High
Brain Hemorrhage 20 57.44 Quite High
Retinal Neovascularization 1 51.60 Quite High
Hematoma 4 51.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another study reported increased MMP-2 and MMP-9 activity and rapid degradation of occludin after temporary focal ischemia (38).
Protein_catabolism (degradation) of occludin associated with ischemia and metalloproteinase
1) Confidence 0.62 Published 2010 Journal Diabetes Section Body Doc Link PMC2797926 Disease Relevance 0.95 Pain Relevance 0.20
VEGF stimulates phosphorylation and redistribution of occludin [19], which is subsequently endocytosed and degraded [47,48].
Protein_catabolism (degraded) of occludin
2) Confidence 0.16 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2533034 Disease Relevance 0.83 Pain Relevance 0.03

General Comments

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