INT245825

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Plg, Serpinf1) extracellular region (Plg, Serpinf1) peptidase activity (Plg)
aging (Serpinf1) cellular_component (Serpinf1)
Anatomy Link Frequency
endothelial cells 2
Plg (Mus musculus)
Serpinf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 2 80.88 Quite High
anesthesia 2 26.96 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 4 98.84 Very High Very High Very High
Injury 2 90.48 High High
Diabetic Retinopathy 2 83.84 Quite High
Retinal Neovascularization 2 82.28 Quite High
Cv Unclassified Under Development 2 80.88 Quite High
Targeted Disruption 4 79.44 Quite High
Diabetes Mellitus 144 73.80 Quite High
Increased Venous Pressure Under Development 2 38.56 Quite Low
Diabetic Macular Edema 22 37.12 Quite Low
Hypoxia 4 21.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results also revealed that rAAV-angiostatin did not upregulate PEDF expression in HUVEC-2C cells.
angiostatin Neg (not) Positive_regulation (upregulate) of Gene_expression (expression) of PEDF
1) Confidence 0.21 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2533034 Disease Relevance 0.85 Pain Relevance 0.04
To further evaluate whether angiostatin could induce the expression of PEDF in endothelial cells, we infected human umbilical vein endothelial cells (HUVEC-2C, Cascade Biologics, Portland, OR) with rAAV-angiostatin.
angiostatin Positive_regulation (induce) of Gene_expression (expression) of PEDF in endothelial cells
2) Confidence 0.18 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2533034 Disease Relevance 0.16 Pain Relevance 0

General Comments

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