INT245929

Context Info Confidence 0.05 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.38 Pain Relevance 0.56

Msg (Mus musculus)

Pain Link Frequency Relevance Heat Glutamate 56 100.00 Nicotine 32 77.84 agonist 36 25.80 Pain 6 5.00 alcohol 6 5.00 Acupuncture 6 5.00 Potency 6 5.00 qutenza 4 5.00 antagonist 4 5.00 medulla 2 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 28 94.40 Pain 6 5.00 Aging 4 5.00 Overdose 2 5.00 Taste Disorders 2 5.00 Body Weight 2 5.00 Blister 2 5.00 Peripheral Arterial Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Effect of MRPs on the CT response to MSG

Positive_regulation (response) of MSG associated with glutamate

1) Confidence 0.05 Published 2008 Journal Chemical Senses Section Body Doc Link PMC2533421 Disease Relevance 0.31 Pain Relevance 0.24

However, at 2.5%, it demonstrated a significant increase in the CT response to MSG.

Positive_regulation (increase) of MSG associated with glutamate

2) Confidence 0.04 Published 2008 Journal Chemical Senses Section Body Doc Link PMC2533421 Disease Relevance 0.07 Pain Relevance 0.33

General Comments

This test has worked.