INT246061

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (KEAP1, NFE2L2) cytoplasm (KEAP1, NFE2L2) cytosol (NFE2L2)
endoplasmic reticulum (KEAP1) nucleolus (KEAP1) plasma membrane (NFE2L2)
KEAP1 (Homo sapiens)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 15 50.00 Quite Low
Lung Cancer 2 41.68 Quite Low
Neuropathic Pain 1 39.96 Quite Low
Diabetes Mellitus 1 38.84 Quite Low
Increased Venous Pressure Under Development 1 38.44 Quite Low
Hypertension 1 37.72 Quite Low
Death 18 5.00 Very Low Very Low Very Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Breast Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of the Nrf2 signaling pathway is tightly regulated by Kelch-like ECH-associated protein 1 (Keap1) according to changes in the intracellular redox state when cells are exposed to exogenous stimuli.
Keap1 Regulation (regulated) of Positive_regulation (Activation) of Nrf2
1) Confidence 0.34 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2535615 Disease Relevance 0 Pain Relevance 0

General Comments

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